Image by Scott Graham



A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma.

Shaban M, Ahmed Raza SE, Hassan M, Jamshed A, Mushtaq S, Loya A, Batis N, Brooks J, Nankivell P, Sharma N, Robinson M, Mehanna H, Khurram SA, Rajpoot N.

J Pathol. 2021 Oct 26. doi: 10.1002/path.5819. Online ahead of print.

PMID: 34698394




Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer.

Presa D, Khurram SA, Zubir AZA, Smarakan S, Cooper PA, Morais GR, Sadiq M, Sutherland M, Loadman PM, McCaul J, Shnyder SD, Patterson LH, Pors K.

Sci Rep. 2021 Sep 23;11(1):18930. doi: 10.1038/s41598-021-98217-z.

PMID: 34556703


Self-regressing oral CD30-positive, EBV-negative, T-cell lymphoproliferative lesions. A poorly understood process highlighted by ominous clinicopathologic features and indolent behavior.

Argyris PP, Ho D, Islam MN, Khurram SA, Courville EL, Morgan S, Sundick B, Soliman M, Janakiram M, Gopalakrishnan R, Koutlas IG.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Jun 7:4638. doi: 10.1016/j.oooo.2021.05.014. PMID: 34526251


Malignant transformation in a cohort of patients with oral epithelial dysplasia.

Hankinson PM, Mohammed-Ali RI, Smith AT, Khurram SA.

Br J Oral Maxillofac Surg. 2021 Mar 3:S0266-4356(21)00085-1. doi: 10.1016/j.bjoms.2021.02.019. PMID: 34303542


Pakistan Oral Cancer Collaborative: analyzing barriers and obstacles to oral cancer diagnosis, treatment, and prevention in Pakistan.

Khokhar MA, Niaz MO, Aslam A, Khan HA, Loya A, Speight PM, Khurram SA.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Sep;132(3):312-319. doi: 10.1016/j.oooo.2021.04.058. PMID: 34284963


Burkitt lymphoma of the head and neck: An international collaborative study.

Arboleda LPA, Rodrigues-Fernandes CI, Mariz BALA, de Andrade BAB, Abrahão AC, Agostini M, Romañach MJ, Pontes HAR, Fonseca FP, Robinson L, van Heerden WFP, Carlos R, Tager EMJR, Hoffmann IL, Cardinalli IA, de Mendonça RMH, de Vasconcelos Carvalho M, Martins-de-Barros AV, Rocha AC, Khurram SA, Speight PM, Lopes MA, Vargas PA, de Almeida OP, Santos-Silva AR.

J Oral Pathol Med. 2021 Jul;50(6):572-586. doi: 10.1111/jop.13209.

PMID: 34091974


Impact of tumor site on the prognosis of salivary gland neoplasms: A systematic review and meta-analysis.

Dos Santos ES, Rodrigues-Fernandes CI, Speight PM, Khurram SA, Alsanie I, Costa Normando AG, Prado-Ribeiro AC, Brandão TB, Kowalski LP, Silva Guerra EN, Lopes MA, Vargas PA, Santos-Silva AR, Leme AFP.

Crit Rev Oncol Hematol. 2021 Jun;162:103352. doi: 10.1016/j.critrevonc.2021.103352.

PMID: 33991662 



Microsecretory Adenocarcinoma of Salivary Glands: An Expanded Series of 24 Cases.

Bishop JA, Sajed DP, Weinreb I, Dickson BC, Bilodeau EA, Agaimy A, Franchi A, Khurram SA, Da Forno P, Robledo J, Kalmar JR, Aguirre S, Krane JF, Tapia JL, Kiss K, Cordell K, Rosebush M, Barrett AW, Oda D, Assaad A, Nagao T, Kawakami F, Nakaguro M, Zahir I, Wakeman K, Ihrler S, Chenevert J, Lin YL, Westra WH, Gagan J, Rooper LM.

Head Neck Pathol. 2021 May 12. doi: 10.1007/s12105-021-01331-7.

PMID: 33982215


Artificial Intelligence-based methods in head and neck cancer diagnosis: an overview.

Mahmood H, Shaban M, Rajpoot N, Khurram SA.

Br J Cancer. 2021 Jun;124(12):1934-1940. doi: 10.1038/s41416-021-01386-x. Epub 2021 Apr 19.

PMID: 33875821 


Convolutional Neural Network-Based Clinical Predictors of Oral Dysplasia: Class Activation Map Analysis of Deep Learning Results.

Camalan S, Mahmood H, Binol H, Araújo ALD, Santos-Silva AR, Vargas PA, Lopes MA, Khurram SA, Gurcan MN.

Cancers (Basel). 2021 Mar 14;13(6):1291. doi: 10.3390/cancers13061291.

PMID: 33799466


Observer agreement in the diagnosis of oral lichen planus using the proposed criteria of the American Academy of Oral and Maxillofacial Pathology.

Idrees M, Farah CS, Khurram SA, Firth N, Soluk-Tekkesin M, Kujan O.

J Oral Pathol Med. 2021 May;50(5):520-527. doi: 10.1111/jop.13170.

PMID: 33730381


Fully digital pathology laboratory routine and remote reporting of oral and maxillofacial diagnosis during the COVID-19 pandemic: a validation study.

Araújo ALD, do Amaral-Silva GK, Pérez-de-Oliveira ME, Gallagher KPD, López de Cáceres CVB, Roza ALOC, Leite AA, Mariz BALA, Rodrigues-Fernandes CI, Fonseca FP, Lopes MA, Speight PM, Khurram SA, Júnior JJ, Martins MD, de Almeida OP, Santos-Silva AR, Vargas PA.

Virchows Arch. 2021 Mar 13:1-11. doi: 10.1007/s00428-021-03075-9. Online ahead of print.

PMID: 33713188


Self-Path: Self-supervision for Classification of Pathology Images with Limited Annotations.

Koohbanani NA, Unnikrishnan B, Khurram SA, Krishnaswamy P, Rajpoot N.

IEEE Trans Med Imaging. 2021 Feb 1;PP. doi: 10.1109/TMI.2021.3056023. Online ahead of print.

PMID: 3352380



Multibeat Echocardiographic Phase Detection Using Deep Neural Networks.

Lane ES, Azarmehr N, Jevsikov J, Howard JP, Shun-shin MJ, Francis DP, Zolgharni M.

Computers in Biology and Medicine.


An optimisation-based iterative approach for speckle tracking echocardiography.

Azarmehr N, Ye X, Howes JD, Docking B, Howard JP, Francis DP, Zolgharni M.

Med Biol Eng Comput. 2020 Jun;58(6):1309-1323. doi: 10.1007/s11517-020-02142-8. Epub 2020 Apr 7.

PMID: 32253607


NUT Carcinoma Arising from the Parotid Gland: A Case Report and Review of the Literature.

Saik WN, Da Forno P, Thway K, Khurram SA.

Head Neck Pathol. 2020 Dec 22. doi: 10.1007/s12105-020-01254-9. Online ahead of print.

PMID: 33351171


Clinicopathological analysis and survival outcomes of primary salivary gland tumors in pediatric patients: A systematic review.

Louredo BVR, Santos-Silva AR, Vargas PA, Ajudarte Lopes M, Martins MD, Guerra ENDS, Prado Ribeiro AC, Brandão TB, de Mendonça RMH, Kowalski LP, Speight PM, Khurram SA, Pérez-de-Oliveira ME.

J Oral Pathol Med. 2020 Dec 12. doi: 10.1111/jop.13151. Online ahead of print.

PMID: 3331434


Automated feature detection in dental periapical radiographs by using deep learning.

Khan HA, Haider MA, Ansari HA, Ishaq H, Kiyani A, Sohail K, Muhammad M, Khurram SA.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 27:S2212-4403(20)31173-1. doi: 10.1016/j.oooo.2020.08.024. Online ahead of print.

PMID: 32950425


The use of digital microscopy as a teaching method for human pathology: a systematic review.

Rodrigues-Fernandes CI, Speight PM, Khurram SA, Araújo ALD, Perez DEDC, Fonseca FP, Lopes MA, de Almeida OP, Vargas PA, Santos-Silva AR.

Virchows Arch. 2020 Oct;477(4):475-486. doi: 10.1007/s00428-020-02908-3. Epub 2020 Aug 24.

PMID: 3283303


Use of artificial intelligence in diagnosis of head and neck precancerous and cancerous lesions: A systematic review.

Mahmood H, Shaban M, Indave BI, Santos-Silva AR, Rajpoot N, Khurram SA.

Oral Oncol. 2020 Nov;110:104885. doi: 10.1016/j.oraloncology.2020.104885. Epub 2020 Jul 13.

PMID: 32674040


The chemokine lymphotactin and its recombinant variants in oral cancer cell regulation.

Abdullah Zubir AZ, Whawell SA, Wong TS, Khurram SA.

Oral Dis. 2020 Nov;26(8):1668-1676. doi: 10.1111/odi.13500. Epub 2020 Jun 30.

PMID: 32562323



An unusual cause of a common presentation: a case of metastatic basal cell carcinoma.

Hankinson P, Collins LHC, Nusrath M, Al-Omari A, Khurram SA.

Br J Oral Maxillofac Surg. 2020 Oct;58(8):1046-1048. doi: 10.1016/j.bjoms.2020.04.037. Epub 2020 May 12.

PMID: 32409129


Oral cancer stem cells drive tumourigenesis through activation of stromal fibroblasts.

Al-Magsoosi MJN, Lambert DW, Khurram SA, Whawell SA.

Oral Dis. 2020 Jun 27. doi: 10.1111/odi.13513. Online ahead of print.

PMID: 32593227


A Novel Digital Score for Abundance of Tumour Infiltrating Lymphocytes Predicts Disease Free Survival in Oral Squamous Cell Carcinoma.

Shaban M, Khurram SA, Fraz MM, Alsubaie N, Masood I, Mushtaq S, Hassan M, Loya A, Rajpoot NM.

Sci Rep. 2019 Sep 16;9(1):13341. doi: 10.1038/s41598-019-49710-z.

PMID: 31527658


Beauty is only mucosa deep: a retrospective analysis of oral lumps and bumps caused by cosmetic fillers.

Martin LHC, Hankinson PM, Khurram SA.

Br Dent J. 2019 Aug;227(4):281-284. doi: 10.1038/s41415-019-0622-y.

PMID: 31444444


Extranodal extension in oral cancer: A role for the nodal microenvironment?

Pilborough AE, Lambert DW, Khurram SA.

J Oral Pathol Med. 2019 Nov;48(10):863-870. doi: 10.1111/jop.12870. Epub 2019 May 21.

PMID: 3108739


Methods for Segmentation and Classification of Digital Microscopy Tissue Images.

Vu QD, Graham S, Kurc T, To MNN, Shaban M, Qaiser T, Koohbanani NA, Khurram SA, Kalpathy-Cramer J, Zhao T, Gupta R, Kwak JT, Rajpoot N, Saltz J, Farahani K.

Front Bioeng Biotechnol. 2019 Apr 2;7:53. doi: 10.3389/fbioe.2019.00053. eCollection 2019.

PMID: 31001524


Characterisation of DOG-1 Expression in Salivary Gland Tumours and Comparison with Myoepithelial Markers.

Khurram SA, Speight PM.

Head Neck Pathol. 2019 Jun;13(2):140-148. doi: 10.1007/s12105-018-0917-3. Epub 2018 Apr 18.

PMID: 29671211


Oral potentially malignant disorders: risk of progression to malignancy.

Speight PM, Khurram SA, Kujan O.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jun;125(6):612-627. doi: 10.1016/j.oooo.2017.12.011. Epub 2017 Dec 29.

PMID: 29396319


Cancer-associated fibroblasts promote bone invasion in oral squamous cell carcinoma.

Elmusrati AA, Pilborough AE, Khurram SA, Lambert DW.

Br J Cancer. 2017 Sep 5;117(6):867-875. doi: 10.1038/bjc.2017.239. Epub 2017 Jul 25.

PMID: 28742795


Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan.

Meisenberg C, Ashour ME, El-Shafie L, Liao C, Hodgson A, Pilborough A, Khurram SA, Downs JA, Ward SE, El-Khamisy SF.

Nucleic Acids Res. 2017 Feb 17;45(3):1159-1176. doi: 10.1093/nar/gkw1026.

PMID: 28180300


Cytogenetic and immunohistochemical characterization of mammary analogue secretory carcinoma of salivary glands.

Khurram SA, Sultan-Khan J, Atkey N, Speight PM.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Dec;122(6):731-742. doi: 10.1016/j.oooo.2016.07.008. Epub 2016 Jul 20.

PMID: 27720350


Accuracy of staging of oral squamous cell carcinoma of the tongue: should incisional biopsy be done before or after magnetic resonance imaging?

Howe TE, Khurram SA, Hunter K, Martin LH, Fry AM.

Br J Oral Maxillofac Surg. 2017 Apr;55(3):298-299. doi: 10.1016/j.bjoms.2016.09.004. Epub 2016 Sep 24.

PMID: 27682718


The chemokine receptors CXCR1 and CXCR2 regulate oral cancer cell behaviour.

Khurram SA, Bingle L, McCabe BM, Farthing PM, Whawell SA.

J Oral Pathol Med. 2014 Oct;43(9):667-74. doi: 10.1111/jop.12191. Epub 2014 Jun 26.

PMID: 24965032


Functional expression of the chemokine receptor XCR1 on oral epithelial cells.

Khurram SA, Whawell SA, Bingle L, Murdoch C, McCabe BM, Farthing PM.

J Pathol. 2010 Jun;221(2):153-63. doi: 10.1002/path.2695.

PMID: 20225245